Suresh Pannerselvam

Suresh Pannerselvam

Computational Scientist, University of Texas Southwestern Medical Center

Publications

A structure-based nomenclature for Bacillus thuringiensis and other bacteria-derived pesticidal proteins

Database, Volume 2022, 2022, baac022 2021

Abstract: In 1998 a nomenclature for the growing list of pesticidal proteins from Bacillus thuringiensis (Bt) was derived based solely on protein sequence comparisons. This nomenclature was widely adopted and provided a robust framework for the naming and classification of the proteins. The success of these proteins in integrated pest management schemes prompted an increased effort to find others with improved or more diverse activities. These discovery activities led to the characterization of proteins from a wider range of bacteria and with a variety of different protein folds. Since most of these new proteins were grouped together as Cry proteins it became apparent that the existing nomenclature had limitations in representing the diverse range of proteins that had been identified. This revised nomenclature retains the basic principles of the 1998 version but provides specific mnemonics to represent different structural groups. For the purposes of consistency, the vast majority of the proteins have either retained their name or have a new name that clearly references the previous one. Other pesticidal proteins not previously included in the nomenclature have been incorporated into this version.

Recommended citation: Neil Crickmore, Colin Berry, Suresh Panneerselvam, Ruchir Mishra, Thomas R Connor, Bryony C Bonning, A structure-based nomenclature for Bacillus thuringiensis and other bacteria-derived pesticidal proteins, JIP 2021-11-22' https://www.sciencedirect.com/science/article/pii/S0022201120301440

A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice

Experimental & molecular medicine 2019

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Recommended citation: Kwon, Hyuk-Kwon; Patra, Mahesh Chandra; Shin, Hyeon-Jun; Gui, Xiangai; Achek, Asma; Panneerselvam, Suresh; Kim, Dong-Jin; Song, Suk-Jong; Hong, Riwon; Kim, Kyoung Soo; ",A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice,Experimental & molecular medicine,51,4,1-19,2019 https://pubmed.ncbi.nlm.nih.gov/28763006/

Cysteine redox state plays a key role in the inter-domain movements of HMGB1: a molecular dynamics simulation study

RSC Advances 2016

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Recommended citation: Panneerselvam, Suresh; Durai, Prasannavenkatesh; Yesudhas, Dhanusha; Achek, Asma; Kwon, Hyuk-Kwon; Choi, Sangdun; ",Cysteine redox state plays a key role in the inter-domain movements of HMGB1: a molecular dynamics simulation study,RSC advances,6,103,100804-100819,2016. https://pubs.rsc.org/en/content/articlelanding/2016/RA/c6ra16343b#!divAbstract

Toll‐like receptor 2 antagonists identified through virtual screening and experimental validation.

The FEBS journal 2016

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Recommended citation: Durai, Prasannavenkatesh; Shin, Hyeon‐Jun; Achek, Asma; Kwon, Hyuk‐Kwon; Govindaraj, Rajiv Gandhi; Panneerselvam, Suresh; Yesudhas, Dhanusha; Choi, Jiwon; No, Kyoung Tai; Choi, Sangdun; ",Toll‐like receptor 2 antagonists identified through virtual screening and experimental validation,The FEBS journal,284,14,2264-2283,2017. https://pubmed.ncbi.nlm.nih.gov/28570013/

Structural mechanism behind distinct efficiency of Oct4/Sox2 proteins in differentially spaced DNA complexes

Public Library of Science 2016

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Recommended citation: Yesudhas, Dhanusha; Anwar, Muhammad Ayaz; Panneerselvam, Suresh; Durai, Prasannavenkatesh; Shah, Masaud; Choi, Sangdun; ",Structural mechanism behind distinct efficiency of Oct4/Sox2 proteins in differentially spaced DNA complexes,PloS one,11,1,,2016. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0147240

Etoposide induces necrosis through p53-mediated antiapoptosis in human kidney proximal tubule cells

Toxicological Sciences 2015

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Recommended citation: Kwon, Hyuk-Kwon; Shin, Hyeon-Jun; Lee, Jae-Hyeok; Park, Seol-Hee; Kwon, Min-Cheol; Panneerselvam, Suresh; Lee, Chan Gyu; Kim, Sang Geon; Kim, Jae-Ho; Choi, Sangdun; ",Etoposide induces necrosis through p53-mediated antiapoptosis in human kidney proximal tubule cells,Toxicological Sciences,148,1,204-219,2015 https://pubmed.ncbi.nlm.nih.gov/26259609/

Inhibition of hyaluronidase by N-acetyl cysteine and glutathione: Role of thiol group in hyaluronan protection

Int J Biol Macromol. 2013

Recommended citation: Sunitha, K; Suresh, P; Santhosh, M Sebastin; Hemshekhar, M; Thushara, RM; Marathe, Gopal K; Thirunavukkarasu, C; Kemparaju, K; Kumar, M Suresh; Girish, KS; ",Inhibition of hyaluronidase by N-acetyl cysteine and glutathione: Role of thiol group in hyaluronan protection, Int J Biol Macromol . 2013 Apr;55:39-46. doi: 10.1016/j.ijbiomac.2012.12.047. Epub 2013 Jan 8. https://pubmed.ncbi.nlm.nih.gov/23305704/

Three dimensional model for N-terminal A domain of DmpR (2-Dimethylphenol) protein based on secondary structure prediction and fold recognition,In silico biology

Insilco Biology 2010

Recommended citation: Suresh, Panneer Selvam; Kumar, Rita; Kumar, Anil; ",Three dimensional model for N-terminal A domain of DmpR (2-Dimethylphenol) protein based on secondary structure prediction and fold recognition,In silico biology,10,"5, 6",223-233,2010 https://content.iospress.com/articles/in-silico-biology/isb00434